中文摘要：

基于聚合物胶束的药物释放系统是一类新型的纳米载体，它同时具有亲水性和疏水性基团，在水中形成胶束，并对药物进行增溶和包裹．对其疏水性内核的筛选有利于携带不同性质的药物；而对其亲水性外壳的设计和优化则能使载药胶束体系逃避单核巨噬细胞的吞噬，赋予其“隐形”性．

英文摘要：

Novel amphiphilic polymers, cholesterol-end-capped poly （2-methacryloyloxyethyl phosphorylcholine） （CMPC） was specially designed as the drug delivery systems. Cytotoxicity of this novel amphiphiles was not observed as indicated by cell culture. Anti-cancer drug adriamycin （ADR） was incorporated into the micelles by oil-in-water method. The release of ADR from the nanosphere continued over 7 d. The drug-loaded micelles could effectively restrain the growth of cancer cell. These results suggest that the drug loaded nanoparticles could be a good candidate for injectable drug delivery carrier.