中文摘要：

目的：探讨组织多普勒Tei指数对先天性心脏病（CHD）患儿右心功能的评定价值。方法：对46例患儿（按肺动脉压力是否升高分为肺动脉高压组及无肺动脉高压组）及33例正常儿分别应用组织多普勒法与血流多普勒法测定右室Tei指数（TDI—Tei指数、PWD—Tei指数）进行对比研究。结果：①与对照组比较，无肺动脉高压组右室PWD—Tei指数及TDI-Tei指数值均升高（0．32±0．05VS0．30±0．04；0．34±0．06VS0．31±0．04），前者差异无统计学意义（P〉0．05），后者差异有统计学意义（P〈0．05）。肺动脉高压组右室PWD—Tei指数及TDI—Tei指数均明显高于无肺动脉高压组（0．51±0．11VS0．32±0．05，P〈0．001；0．55±0．12vs0．34±0．06，P〈0．001）。②各组内右室PWD—Tei指数、TDI—Tei指数间均具有良好的相关性。③患病组右室TDI—Tei指数较PWD—Tei指数与PASP间的相关性更佳（r=0．86，P〈0．001 vs r=0．79，P〈0．001）。TDI—Tei指数评判CHD患儿肺动脉高压的敏感度及特异度均高于PWD—Tei指数（敏感度：78％VS71％；特异度：90％VS87％）。结论：组织多普勒Tei指数可较敏感的反映CHD患儿的右心功能变化，是评价右室整体功能的较好指标，且可提示CHD患儿合并肺动脉高压的存在与否。

英文摘要：

Objective： To explore the value of right ventricular function evaluation in tissue Doppler - derived Tei index （ TDI - Tei） in children with congenital heart disease （CI-ID） . Methods： The right ventricular Tel indexes （TDI -Tei index and PWD -Tei index） of 46 CHD children （ divided into pulmonary hypertension group and non - pulmonary hypertension group according to their pulmonary arterial systolic pressure ） and 33 healthy children were measured by tissue Doppler method and Doppler flow imaging method and compared. Results： （1）The right ventricular PWD - Tei index in non - pulmonary hypertension group was higher than that in control group （ 0. 32 ± 0. 05 vs 0. 30 ± 0. 04 ）, without significant difference （ P 〉 0. 05 ） ; the right ventricular DTI - Tei index in non - pulmonary hypertension group was higher than that in control group （ 0. 34 ± 0. 06 vs 0. 31±0. 04） （ P 〈 0. 05 ） . The right ventricular PWD - Tei index and DTI - Tei index in pulmonary hypertension group were higher than those in non - pulmonary hypertension group （0. 51 ± 0. 11 vs 0. 32± 0.05, P 〈 0. 001 ; 0. 55± 0. 12 vs 0. 34 ± 0. 06, P 〈 0. 001 ） . （2）There was correlation between right ventricular PWD - Tei index and DTI - Tei index in each group. （3）Compared with right ventricular PWD - Tei index （ T = 0. 79, P 〈 0. 001 ）, a better correlation was observed between right ventricular TDI - Tei index and pulmonary arterial systolic pressure （ T = 0. 86, P 〈 0. 001 ） . For evaluating pulmonary hypertension of CHD children, the sensitivity and specificity of DTI - Tei index were higher than those of PWD - Tei index （ sensitivity ： 78% vs 71% ; specificity： 90% vs 87% ） . Conclusion： Tissue Doppler -derived Tei index can reflect the changes of right ventricular function of CHD children sensitively, which is a useful index for evaluating total function of right ventricle and indicative index of CHD children combined with pulmonary hypertension or not.