中文摘要：

目的：探讨拉萨藏族青少年骨发育水平的变化趋势，为临床应用骨龄提供科学依据。 方法：于2003—07／09采用分层整群抽样调查，从拉萨市6所大、中、小学随机选取父母为藏族，本人在拉萨生活，经体检证明健康的7-21岁青少年为调查对象。按性别分组，每岁为1组，共调查1496名，男743名，女753名。按Fels法进行手腕部骨龄评价，并进行骨龄与年龄的相关分析和骨龄性别差异分析. 结果：共调查1496名，数据均进入结果分析。①Fels法评价手腕部骨龄结果：各年龄组骨龄均小于年龄，男性7-21岁各年龄组年龄与骨龄差值变化分别为：1.17±1．18，1．28±1．06，1．79±1．13，1．99±1．05,1．87±1．73，1．72±1．80．1．22±1．68．1．20±1.43，1．29±1．02，1．37±1．27，14.9 ±0．98，1.71±1.11，2．05±0．79．2．72±0．55；女性分别为：1．18±1．00，1．40±1．28．1．17±1．46，0．95±141, 0.43±1．34．0．55±1．23，1.29±1．16，1．59±0．95，1.48±1．19，2．15±0．98．2．46±1．06，2．92±0．75,3.60±0．33，4．48±0．26。骨龄性别差异表现为：7-8岁年龄组骨龄男性大于女性，9～12岁年龄组骨龄男性小于女性，而后呈现男性又大于女性。②骨龄与年龄的相关分析：骨龄与年龄呈高度正相关（男性r=0.947，女性r=-0．928．总体r=-0．934）。 结论：各年龄组骨龄均小于年龄．提示拉萨藏族青少年骨发育具有延缓的特点．这可能是西藏典型的高寒、缺氧等高原环境造成的。Fels法可以用于评价拉萨藏族青少年手腕部骨龄，但不完全适用，因此有必要制定西藏藏族儿童青少年的骨龄标准。

英文摘要：

AIM： To investigate the trend of skeletal development of Tibetan adolescent in Lhasa, and to provide scientific evidence for the application of skeletal age in clinic. METHODS： From July to September 2003, totally 1 496 healthy adolescents （743 males and 753 females） living in Lhasa, aged 7 to 21 years, whose parents were Tibetan, were randomly selected from 6 universities, middle schools and elementary schools. They were investigated with stratified cluster sampling and grouped according to gender and age （every age was one group）. The skeletal age of hand-wrist was measured with the Fels method and the correlation between skeletal age and chronological age and the gender difference of skeletal age were analyzed. RESULTS： Totally 1 496 subjects were investigated, and all the data were involved in the analysis of results. ①The results of skeletal age of hand-wrist assessed with the Fels method： The skeletal age was smaller than chronological age in all age groups： The changes of different value between chronological age and skeletal age in females aged from 7 to 21 years： 1.17±1.18, 1.28±1.06, 1.79±1.13, 1.99±1.05, 1.87±1.73, 1.72±1.80, 1.22±1.68, 1.20±1.43. 1.29±1.02, 1.37±1.27, 1.49±0.98, 1.71±1.11, 2.05±0.79 and 2.72±0.55, respectively, and those in females were 1.18±1.00, 1.40±1.28, 1.17±1.46, 0.95±1.41, 0.43±1.34, 0.55±1.23, 1.29±1.16, 1.59±0.95, 1.48±1.19, 2.15±0.98, 2.46±1.06. 2.92±0.75, 3.60±0.33 and 4.48±0.26, respectively. Gender difference of skeletal age： h was older in males than in females in the 7 to 8 years old groups and 13 to 21 years old groups, but younger in males than in females in the 9 to 12 years old groups. ②Correlation between skeletal age and chronological age： The skeletal age and chronological age presented highly positive correlation, （male： r=0.947, female： r=0.928, totally： r=0.934）. CONCLUSION： The skeletal age was younger than chronological age in all age groups, indicating that the skeletal development o