中文摘要：

直到现在，粉刺 vulgaris 的病原学仍然是不明确的。尽管临床医生们通常否认在 Demodex 群袭和粉刺 vulgaris 之间的协会，它在一些临床的惯例被证明了。证实在 Demodex 群袭和粉刺 vulgaris 之间的协会，元分析被进行。预定义的选择标准被使用寻找在知识， MEDLINE，和中国知识基础结构(CNKI ) 的 ISI 网分析了在 Demodex 群袭和粉刺 vulgaris (到 2011 年 8 月的 1950 年 1 月) 之间的协会的所有出版报纸数据库。元分析被执行基于固定效果模型或随机的效果模型计算机会比率(ORs ) 和 95% 信心间隔(CI ) 。我们注册了在这元分析的报纸，包括学生和居民在中国和 42 130 个参加者盖住土耳其和 25 个不同省 / 自治市，从 1 ～ 78 年变老的 60 汉语和 3 英语。分享或在随机的效果模型是 2.80 (95% CI， 2.343.36 ) 。稳定性根据敏感分析是柔韧的。设有自动保险装置数字是 18 477，建议有否定结论的至少 18 477 篇文章将被需要颠倒粉刺 vulgaris 与 Demodex 群袭有关的结论。出版偏爱的效果因此是不足道的并且能被忽略。粉刺 vulgaris 与 Demodex 群袭被联系，这被结束。这显示当为粉刺 vulgaris 的常规治疗是无效的时， Demodex 螨和必要 acaricidal 治疗的检查应该被考虑。

英文摘要：

Until now, etiology of acne vulgaris is still uncertain. Although clinicians usually deny the association between Demodex infestation and acne vulgaris, it has been proved in some clinical practices. To confirm the association between Demodex infestation and acne vulgaris, a meta-analysis was conducted. Predefined selection criteria were applied to search all published papers that analyzed the association between Demodex infestation and acne vulgaris （January 1950 to August 2011） in ISI Web of Knowledge, MEDLINE, and China National Knowledge Infrastructure （CNKI） databases. A meta-analysis was performed to calculate odds ratios （ORs） and 95% confidence intervals （CIs） based on fixed effects models or random effects models. We enrolled the 60 Chinese and 3 English papers in this meta-analysis, which covered Turkey and 25 different provinces/municipalities in China and 42130 participants in- cluding students and residents, aged from 1 to 78 years. The pooled OR in random effects models is 2.80 （95% CI, 2.34-3.36）. Stability is robust according to sensitivity analysis. The fail-safe number is 18 477, suggesting that at least 18477 articles with negative conclusions would be needed to reverse the conclusion that acne vulgaris was related to Demodex infestation. So the effect of publication bias was insignificant and could be ignored. It was concluded that acne vulgaris is associated with Demodex infestation. This indicates that when regular treatments for acne vulgaris are ineffective, examination of Demodex mites and necessary acaricidal therapies should be considered.