中文摘要：

以芳基硼酸为芳基化试剂,以Pd（PPh3）4为催化剂,Cu I为添加剂,哌啶为碱,在DMF中于125℃反应24 h,通过C—H键的活化反应,合成了系列C-8位芳基取代的嘌呤类似物,为该类化合物的合成提供了新的合成路线.

英文摘要：

C-8 aryl substituted purine analogues were successfully synthesized by direct C--H activation ofpurines with aryl boric acids catalyzed by Pd（PPh3）4 in the presence of CuI and piperidine in DMF at 125 ℃ for 24 h, providing a new process for the symhesis of 8-aryl purines.