RASSF基因家族(即Ras相关区域家族)由10个成员组成,分别为RASSF1-RASSF10。此家族的多个基因参与细胞增殖、分化、转移及凋亡等多种生物学过程。RASSF基因家族的研究已成为国内外研究的热点,本文将就RASSF基因家族在肿瘤中的主要作用机制做简要综述。
RASSF gene family (Ras related area family),multiple genes from RASSF1 to RASSF10 of the gene family participates in many biological processes including cell proliferation,differentiation,metastasis and apoptosis. The research of RASSF gene family has become a hot field in the world. The mechanism of action of RASSF gene family in tumor are briefly reviewed in this article.