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儿童脊柱侧凸非融合手术治疗的发展及现状
  • ISSN号:2095-4344
  • 期刊名称:《中国组织工程研究》
  • 时间:0
  • 分类:R318[医药卫生—生物医学工程;医药卫生—基础医学]
  • 作者机构:[1]山西医科大学第二临床医学院,山西省太原市030001, [2]山西医科大学第二医院骨科,山西省太原市030001, [3]山西医科大学第二医院骨与软组织损伤修复山西省重点实验室,山西省太原市030001
  • 相关基金:国家自然科学基金“诱导性IHH基因对软骨退变治疗作用的研究”(81071495);国家自然科学家基金“在体观察过度应力负荷对大鼠关节软骨损伤作用及机制研究”(81000815);山西省基础研究项目“玻璃化冷冻技术在维持关节软骨细胞生物学特性中的作用研究”(2012011046-8)~~
中文摘要:

背景:儿童脊柱侧凸的治疗是脊柱外科的挑战之一,外科手术治疗尚没有满意的方法. 目的:综述儿童脊柱侧凸外科治疗方法的发展及现状,分析各种方法的利弊,展望儿童脊柱侧凸非融合手术治疗的发展. 方法:以“Scoliosis,Infantile scoliosis,Juvenile scoliosis,fusionless surgery,spinal implant”为英文检索词,“脊柱侧凸,少儿型脊柱侧凸,青少年型脊柱侧凸,脊柱内固定器,脊柱侧凸非融合手术”为中文检索词,检索Pubmed数据库、CNKI数据库2001至2012年发表的相关文献.共检索到113篇文献,排除无关重复的文献,保留36篇进行综述. 结果与结论:目前脊柱侧凸外科治疗主要方法中,撑开技术可以保证脊柱的生长但需要不断的后期延长,生长导向技术可以避免不断的延长手术,但脊柱的生长不能得到保证,也不能纠正脊柱的旋转畸形;而生长调节技术对脊柱畸形的纠正有一定的作用,但它对严重脊柱畸形的作用是不确定的;可生长三维矫形技术的动物实验证明既能保证脊柱的生长,同时能纠正脊柱的旋转,术后不需要不断地延长,理论上是较理想的治疗方法,需要临床研究验证.

英文摘要:

BACKGROUND:Treatment of scoliosis in children is a chal enging in spinal surgery. To date, there is no satisfactory surgical method for the treatment of scoliosis in children. OBJECTIVE:To review the development and current situation of the non-fusion surgery for the treatment of children with scoliosis, to analyze the pros and cons of various methods and to prospect the future. METHODS:The PubMed database and CNKI database from 2001 to 2012 were retrieved by computer with the key words of“scoliosis, infantile scoliosis, juvenile scoliosis, fusionless surgery, spinal implant”in English and Chinese. A total of 113 literatures were screened out, and then the repetitive and irrelevant researches were eliminated, then 36 literatures were included for the final review. RESULTS AND CONCLUSION:To date, among the main methods of scoliosis surgery, lengthening technology can guarantee the growth of the spine, but subsequent lengthening surgery was needed;growth guiding technology could avoid subsequent lengthening surgery, but the growth of spine could not be guaranteed and could not correct the rotational deformity of spine;growth regulating technology could correct deformity, but the capacity of serious spinal deformity was indeterminacy;animal experiment of automatic growth three-dimensional orthopaedic technology has demonstrated that it could guarantee the growth of the spine, and could correct the deformity at the same time without subsequent lengthening surgery. Theoretical y, automatic growth three-dimensional orthopaedic technology is the perfect solution for children scoliosis, but it stil needs clinical checking.

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期刊信息
  • 《中国组织工程研究》
  • 北大核心期刊(2014版)
  • 主管单位:中华人民共和国卫生和计划生育委员会
  • 主办单位:中国康复医学会 《中国组织工程研究》杂志社
  • 主编:唐佩福
  • 地址:沈阳浑南新区10002邮政信箱
  • 邮编:110180
  • 邮箱:crter3377@163.com
  • 电话:024-31416864
  • 国际标准刊号:ISSN:2095-4344
  • 国内统一刊号:ISSN:21-1581/R
  • 邮发代号:8-584
  • 获奖情况:
  • 2001“百种中国杰出学术期刊,卫生部首届医药卫生优秀获奖期刊,北方优秀期刊,辽宁省一级期刊,第三、四届沈阳市优秀期刊一等奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),荷兰文摘与引文数据库,荷兰医学文摘,中国中国科技核心期刊,中国北大核心期刊(2008版),中国北大核心期刊(2014版)
  • 被引量:16688