中文摘要：

目的探讨分析骨科创面蜡样芽胞杆菌的感染情况,研究其耐药性及临床特点,为患者治疗提供参考依据。方法随机选取2011年6月-2013年6月收入的30例骨科创面蜡样芽胞杆菌感染患者作为观察组,同期选取30名健康人作为对照组,比较两组受试人员临床特点及耐药性,数据采用SPSS 19.0软件进行统计分析。结果观察组的30例患者中23例发生创面感染,感染率为76.7%;实验室检查结果显示,观察组患者的总蛋白含量为（49.94±8.24）g/L,低于对照组的（69.57±2.60）g/L,差异有统计学意义（P〈0.05）;观察组患者对亚胺培南、环丙沙星、万古霉素等抗菌药物的耐药率〈15.0%,对青霉素G、头孢唑林等其他抗菌药物的耐药率较高,均〉80.0%。结论蜡样芽胞杆菌感染患者常伴营养不良、免疫力低下,且发生开放性骨折、创面污染的患者易发生感染;应对症给予患者支持治疗,酌情补充白蛋白,依据药敏试验结果,择优选择抗菌药物进行治疗。

英文摘要：

OBJECTIVE To investigate the situation of orthopedic wound with Bacillus cereus infections and observe the drug resistance and clinical characteristics so as to provide guidance for clinical treatment .METHODS From Jun 2011 to Jun 2013 ,totally 30 patients with orthopedic wounds with B .cereus infections were randomly chosen as the observation group ,meanwhile ,30 healthy people were set as the control group .The clinical characteristics and drug resistance were compared between the two groups of participants ,and the statistical analysis of data was performed with the use of SPSS 19 .0 software .RESULTS Of 30 patients in the observation group ,23 cases had the wound infections ,with the infection rate of 76 .7% .The results of the laboratory examination indicated that the total protein content of the observation group was （49 .94 ± 8 .24）g/L ,lower than （69 .57 ± 2 .60） g/L of the control group ,and the difference was significant （P〈0 .05） .Among the patients of the observation group ,the drug resistance rates to imipenem ,ciprofloxacin ,and vancomycin were less than 15 .0% ,while the drug resistance rates to penicillin G and cefazolin were more than 80 .0% .CONCLUSION The patients with B .cereus infection are usually characterized by malnutrition ,low immunity ,and open fractures ;the patients with wound contamination tend to have the infections .It is necessary to conduct the symptomatic treatment ,appropriately supplement the al‐bumin ,and reasonably use antibiotics based on the results of the drug susceptibility testing .