中文摘要：

目的对葫芦科栝楼属植物栝楼果实瓜蒌体积分数为90％的乙醇提取物的正丁醇萃取部分进行化学成分研究。方法利用硅胶、反相中低压、凝胶Sephadex LH-20柱色谱以及制备型高效液相色谱等手段进行分离纯化，并通过理化性质和各种波谱数据对这些化合物进行结构鉴定。结果从瓜蒌的正丁醇萃取部位分离得到4个化合物，分别鉴定为2，5-二羟甲基呋喃（furan-2，5-diyldim—ethanol，1）、柯伊利素-7-O-β-D-葡萄糖苷（chrysoerid-7-O-β-D—glucoside，2）、苹果酸丁二酯（dibutyl-2-hydroxysuccinate，3）、（2，2＇-Bioxazolidine）-3，3’-diethanol（4）。结论这4个化合物均为首次从该属植物中分离得到，其中化合物4是新天然产物。

英文摘要：

Objective To isolate and identify the chemical constituents of the butanol extract part of the fruit of Trichosanthes kirilowii Maxim. ethanol extract. Methods The chemical constituents of T kirilowii Maxim. were studied by multiple chromatographical techniques （ such as silica gel chromatography, Sephadex LH-20, prepretion HPLC, and etc. ） and these compounds were identified by analysis of the spectral data and chemical properties. Results On the basis of physio-chemical evidence and spectral analysis, the structures of the 4 compounds were identified as follows： furan-2,5-diyldimethanol （ 1 ）, chrysoerid-7-O-fl-D-glucoside （ 2 ）, dibutyl 2-hydroxysuccinate （ 3 ）, 12,2 ＇-Bioxazolidine ] -3,3 ＇-diethanol （ 4 ）. Conclusions All the mentioned compounds are isolated from this genus for the first time, and compound 4 is isolated from natural products for the first time.