中文摘要：

目的评价采用ProGlide封堵器实施经皮穿刺主动脉腔内修复术的疗效，总结术后常见并发症的预防和处理方法。方法回顾性分析2012年12月至2013年5月完成的116例经皮穿刺主动脉腔内修复术的围手术期并发症及处理情况。结果主动脉腔内修复手术即刻技术成功率99．1％（115／116）。共封堵150处股动脉入路，其中封堵20F-25F血管鞘99例次，18F以下血管鞘51例次，封堵失败导致穿刺点出血7例，3例行手术探查止血，4例局部压迫并加压包扎止血；入路动脉闭塞6例，其中斑块翻起形成夹层5例，穿刺点动脉狭窄1例，均行手术探查并重新缝合。血管封堵器1次成功率85．3％（128／150），2次成功率91．3％（137／150）。术后蓝趾综合征11例，发生率7．3％（11／150）。围手术期无死亡等严重并发症。术后平均住院时间为（4．3±1.7）d。结论经皮穿刺实施主动脉病变腔内修复术时，使用Perclose ProGlide封堵器安全有效。

英文摘要：

Objective To evaluate the safety and efficacy of the ProGlide closure system after percutaneous placement of aortic endografts. Methods From December 2012 to May 2013, clinical data of 116 cases with endovascular stent-graft therapy and percutaneous closure technique were analyzed retrospectively. Results The technical success rate of endovascular therapy was 99. 1% （115/116）. Hemostasis was achieved using multiple ProGlide device in a total of 150 femoral sites required for large-bore sheaths insertion, including 20 -25 F access sites （n = 99） and 〈 18 F access sites （n = 51）. In 7 patients, ProGlide devices failed to achieve hemostasis, leading to ongoing bleeding requiring prolonged additional compression （n = 4） and surgical repair （ n = 3 ）. In 6 patients, ProGlide devices caused the stenosis or occlusion in the puncture site as a result of the suture pursing the artery too tightly （ n = 1 ） and local dissection （ n = 5 ） , which were treated with surgical repair. The initial technical success rate for the ProGlide closure devices was 85.3% （128/150） , and the secondary technical success rate was 91.3% （137/150）. Blue toe syndrome was observed in 7.3% （11/150）. There was no perioperative mortality and the mean postoperative in-hospital stay was 4. 3 ± 1.7 days. Conclusions Pereutaneous closure technique using multiple Perclose ProGlide devices is safe and effective in endovascular stent-graft treatment of aortic disease.