目的探讨低血糖指数糖尿病膳食对2型糖尿病患者糖脂代谢的影响。方法选取门诊治疗2型糖尿病患者74例,随机分为研究组和对照组,两组患者均予以相同的药物控制血糖。对照组予以传统的糖尿病饮食知识教育和普通糖尿病食谱,研究组予以低血糖饮食知识教育和低血糖膳食食谱。观察并比较两组患者干预前和8周后血糖和血脂控制情况的变化。结果干预8周后,两组患者FBG、2 h PG和Hb A1c均较前明显下降(P〈0.05或P〈0.01),且研究组下降值明显大于对照组(P〈0.05);同时两组患者TC、TG和LDL-C水平均较前明显下降、HDL-C水平较前明显上升(P〈0.05或P〈0.01)。且研究组下降或上升值明显大于对照组(P〈0.05)。对照组和研究组分别发生低血糖事件8例和2例,研究组低血糖事件发生率明显低于对照组(χ2=4.16,P〈0.05)。结论低血糖指数糖尿病膳食用于2型糖尿病具有较好的效果,对患者的糖脂代谢具有较大的改善作用,有利于血糖及糖化血红蛋白的控制,降低低血糖事件发生率,并能调节血脂水平,改善患者血脂谱和预后。
Objective To discuss influence of low glycemic index(GI) diet on glucose and lipid metabolism of patients with type 2 diabetes. Methods A total of 74 cases of patients with type 2 diabetes, who were given medical treatment at outpatient, were divided into research group and control group at random. The patients in two groups were given the same drugs to control blood sugar. The patients in control group were given traditional diet knowledge education and ordinary recipe of diabetes, while the patients in research group were given low glycemic diet knowledge education and recipe. The changes of blood sugar and blood fat control of patients in two groups before intervention and 8 weeks after intervention were observed and compared. Results After 8 weeks’ intervention, FBG, 2 h PG and Hb A1 c of patients in two groups were obviously declined than before(P〈0.05 or P〈0.01), and the declining rate of patients in research group was much higher than that in control group. Meanwhile, TC, TG and LDL-C levels of patients in two groups were obviously declined than before, while HDL-C level were obviously rose than before(P〈0.05 or P〈0.01), and the declining or rising rate of patients in research group were much higher than those in control group(P〈0.05). 8 and 2 cases of glucopenia occurrences were appeared in control group and research group respectively, and the glucopenia occurrence rate of patients in research group was much lower than that in control group(χ2=4.16, P〈0.05). Conclusion Low GI diet has favorable curative effect on patients with type 2 diabetes, and great improvement effect on glucose and lipid metabolism of patients, which is favorable for the control of blood sugar and glycosylated hemoglobin, can reduce the glucopenia occurrence rate, adjust blood fat level, and improve blood lipid profile and prognosis.