中文摘要：

NTrifluoromethyl 和 cyclopropyl 代替了 2-isoxazolines 与 hydroxylamine 经由 -trifluoromethyl-/-cyclopropyl-substituted enones 的支持 DBU 的牙齿反应被综合。牙齿反应由迈克尔增加和跟随的环合组成。大量 3 代用品 5-cyclopropyl-5- trifluoromethyl-2-isoxazolines 被获得在对在温和反应条件下面的优秀收益好。方法能也适用于另外的代替 trifluoromethyl 的 enones。

英文摘要：

NTrifluoromethyl and cyclopropyl substituted 2-isoxazolines were synthesized via a DBU-promoted domino reaction of β-trifluoromethyl-/β-cyclopropyl-substituted enones with hydroxylamine. The domino reaction consists of a Michael addition and the followed cyclization. A wide range of 3-substituted 5-cyclopropyl-5-trifluoromethyl-2-isoxazolines were obtained in good to excellent yields under mild reaction conditions. The method could also apply to other trifluoromethyl-substituted enones.