本文综述了近10年来手性二茂铁类配体在钯催化不对称烯丙基取代反应,包括各种不同底物的烯丙基烷基化、烯丙基胺基化和烯丙基磺酰化反应中的应用,并对其在不对称Claisen重排、不对称Diels-Alder反应、不对称Heck反应、不对称羰基化、不对称氢化硅烷化和不对称碳碳键断裂等反应中的应用进行了综述,对部分反应的机理和该领域的发展前景进行了讨论。
This article briefly describes recent progress on palladium- catalyzed reactions using chiral ferrocene ligands, including allylic alkylation, allylic amination asymmetric allylic substitution and allylic sulfonylation. The Claisen rearrangement, Diels-Alder reaction, Heck reaction, asymmetric carbonylation, asymmetric hydrosilylation and C-C bond cleavage using chiral ferrocene ligands as catalyst are also reviewed. Some reaction mechanisms and perspective are discussed.