中文摘要：

近年来,调节性B淋巴细胞（regulatory B cells,Bregs）与慢性炎症、自身免疫及移植耐受等疾病关系的研究越来越多,其在肝脏疾病中的作用也逐渐引起广大学者的关注,了解Breg细胞在肝炎、肝癌、自身免疫性肝病等疾病发生发展中的作用,可为治疗提供新的研究方向。本文在总结了Breg细胞的基本生物学功能的基础上,主要阐述了Breg细胞在肝脏疾病方面的研究进展。

英文摘要：

During the past few years, a series of studies have revealed that the regulatory B cells（Bregs） playsignificant roles in many diseases, such as chronic inflammation, transplantation and autoimmune diseases. Hence,more and more researchers have paid attention to its function in liver diseases. Better understanding the role ofBregs in virus hepatitis, hepatoma, autoimmune liver diseases will provide a new promising treatment target. In thisreview, we focus on the recent advances that lead to the understanding of the function of Bregs and the implicationsof Bregs in liver diseases.