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膝关节腔注射透明质酸钠结合运动疗法治疗膝骨关节炎的临床研究
  • ISSN号:1005-0205
  • 期刊名称:中国中医骨伤科杂志
  • 时间:2013.10
  • 页码:17-19
  • 分类:R684.3[医药卫生—骨科学;医药卫生—临床医学;医药卫生—外科学]
  • 作者机构:[1]上海市第七人民医院骨伤康复科,上海200137, [2]上海市岳阳中西医结合医院骨伤科
  • 相关基金:国家自然科学基金资助项目(编号:81173357)上海市体育局资助项目(编号:30304113240)上海市卫生局资助项目(编号:2008L043A)上海市体育局资助项目(编号:30304113205)
  • 相关项目:基于整合素介导的力学信号转导途径研究手法治疗膝骨关节炎的作用机制
中文摘要:

目的:观察关节腔内注射透明质酸钠结合运动疗法治疗膝骨性关节炎的临床疗效并对疗效进行评价。方法:将90例膝骨关节炎患者随机分成治疗组及对照组(非甾体抗炎药物组),两组均治疗30d,以总有效率、wOMAC量表评分和Irrgang量表评分为观察指标。结果:总有效率:两组间治疗前后比较差异无统计学意义(P〉0.05)。WOMAC量表评分和Irrgang量表评分:两组内治疗前后总分评分、两组间治疗前后总分、两组间治疗前后疼痛、症状评分比较差异均无统计学意义(P〉0.05);但两组间治疗前后僵硬、躯体功能、生活功能评分比较差异均有统计学意义(P〈0.05),治疗组优于对照组。结论:膝关节腔内注射透明质酸钠结合运动疗法治疗膝骨关节炎安全、有效,可以改善患者疼痛症状,且对僵硬、躯体功能生活功能的改善较药物组明显。WOMAC量表和Irrgang量表可作为临床治疗膝关节骨关节炎疗效评价的有效量化指标。

英文摘要:

Objective:To observe the clinical curative effect of knee injection with sodium hyaluronate and exercise therapy on knee osteoarthritis and assess the results. Methods: 90 patients with knee osteoarthritis were randomly divided into treatment group and control group (group of non-steroidal anti-inflammatory drugs), both group were treated for 30 days, the total effective rate, WOMAC scale score and Irrgang scale score as observation. Results:Total effective rate: there was no significant difference between the two groups before and after treatment (P〉0.05). WOMAC questionnaire score and Irrgang rating scale: total score before and after the treatment in two groups, scores between the two groups before and after treatment, pain and symptom scores before and after treatment between the two groups had no significant difference (P〉0.05). But there was significant difference before and after treatment between two groups in stiffness, physical function, functional score (P〈0.05), treatment group was superior to control group. Conclusion:Knee joint cavity injection of sodium hyaluronate combined with exercise therapy for knee osteoarthritis is safe, ideal and effective, can improve the patients pain symptoms, and on the improvement of the stiffness, the Physical function and life functions significantly better than the drug group. WOMAC questionnaire and Irrgang scale can be used as the effective evaluation indicators in the clinical treatment of knee osteoarthritis.

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期刊信息
  • 《中国中医骨伤科杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中华中医药学会 湖北省中医药研究院
  • 主编:李同生
  • 地址:武汉市珞瑜路856号
  • 邮编:430074
  • 邮箱:admin@totcm.org
  • 电话:027-87409653
  • 国际标准刊号:ISSN:1005-0205
  • 国内统一刊号:ISSN:42-1340/R
  • 邮发代号:38-182
  • 获奖情况:
  • 中国科学技术学会择优资助高科技期刊,国家自然科学基金委择优资助高科技期刊,中国科学引文数据库来源期刊,中国学术综合评价数据库来源期刊,中国期刊网、中国学术期刊期刊光盘版全文收录期刊,国际科技部中国科技论文统计源期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),中国中国科技核心期刊
  • 被引量:15410