中文摘要：

红霉素菌渣是宝贵的资源,但却含有少量的红霉素残留,潜在引发环境细菌耐药的风险,被国家定义为危险废物。文章采用厌氧发酵技术处理红霉素菌渣,拟借助微生物作用降低抗生素残留并制取生物燃气,文中考察了红霉素残留随厌氧发酵过程的降解规律。研究发现：中温（35℃）发酵、接种比为0.4、含固率为8%时,单位池容产气率最高,红霉素菌渣的厌氧发酵处理是可行的。此外,在发酵的10 d后,红霉素降解率达到94%以上,日相对降解率与发酵液pH相关,pH越小降解速率越大,pH越接近中性,降解越缓慢。同时得到其降解过程与厌氧发酵产气量无明显相关性。该文为红霉素菌渣安全资源化提供了基础数据。

英文摘要：

Erythromycin mycelial dreg is a valuable resource, but it was defined as hazardous waste in China because of the residual Erythromycin which causes the potential environmental risk of bacterial drug resistance. In this study, anaerobic digestion was used to treat Erythromycin mycelial dreg, aiming at decrease of the residual Erythromycin and preparation of biogas by means of microbial action. Degradation rules of the residual Erythromycin during this process was also investigated. The study results showed that the gas production of unit pool volume reached to the highest value under the conditions of mesophilic fermentation at 35℃, inoculation ratio of 0.4 and solid content of 8%. Therefore, Erythromycin mycelial dreg was feasible for anaerobic digestion. Additionally, after10 days for anaerobic digestion, the degradation rate exceeded 94%. Daily relative degradation rate was related to pH of the digested effluent. The degradation rate increased with the decrease of pH value. The residual Erythromycin was degraded more slowly when pH got close to be neutral. Meanwhile, there was no significant correlation between degradation process and gas production. The study provided valuable basic data for environment-friendly disposal of Erythromycin mycelial dreg.