中文摘要：

目的对高血压患者的血浆同型半胱氨酸（Hcy）与年龄（Age）、性别（Sex）、血脂及血浆尿酸（UA）的相关性进行分析研究。方法依托社区综合防治项目,采用生化酶法对2 350名高血压患者,其中男1 190人,女1 160人,进行血浆同型半胱氨酸、尿酸（UA）、甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白（LDL）检测,并采用多元回归方法进行相关性分析。结果统计显示年龄、性别和尿酸对Hcy的影响差异有统计学意义,而TC、TG和LDL对Hcy无影响。年龄每增加1岁,log（Hcy）平均增加0.0055μmol/L;和男性相比,女性log（Hcy）平均低0.324μmol/L;UA每增加1μmol/L,log（Hcy）增加0.0005μmol/L。结论一定范围内,同型半胱氨酸与尿酸呈正相关,与TC、TG和LDL未发现明显相关。

英文摘要：

Objective To analyze the correlations of age,gender,blood uric acid（UA） and lipids with plasma homocysteine（Hcy） in hypertensive patients.Methods Based on a community-based comprehensive hypertension prevention and control project,plasma concentrations of Hcy,UA,triglycerides,total cholesterol（TC） and low-density lipoprotein（LDL）were detected by biochemical enzymatic assay in 2,350 hypertensive patients（1,190 males and 1,160 females）.Their correlations with Hcy were analyzed by multiple linear regression.Results Age,gender and UA were statistically correlated withHcy,while TC,TG and LDL were not.The value of log（Hcy）increased by 0.0055μmol/L with one year increase of age andby 0.0005μmol/L with 1μmol/L increase of UA.Compared with that of the males,the average value of log（Hcy）was 0.324μmol/L lower than that of the females.Conclusions Uric acid has a positive correlation with Hcy in a certain range,while TC,TG and LDL don’t have significant correlations with Hcy.