目的 评估含银离子抗菌敷贴能否有效降低肝脏术后手术切口感染率。方法 采取前瞻性研究方法,对2011年1月至2015年12月在徐州市中心医院肿瘤外科行肝脏手术的患者在手术结束时随机使用含银离子敷贴(含银离子敷贴组,入选105例,退出4例,进入实验101例)和普通无菌纱布(普通无菌纱布组,入选116例,退出6例,进入实验110例)覆盖切口。观察对比两组术后切口愈合情况。结果 110例使用普通无菌纱布的患者中,共有16例出现不同程度的手术切口感染,发生率为14.55%;而101例使用含银离子敷贴的患者中只有5例出现手术切口感染,发生率为4.95%,两组之间差异有统计学意义(P〈0.05)。感染手术切口共培养革兰阳性(G+)细菌11株,革兰阴性(G-)细菌10株,其中最常见的是金黄色葡萄球菌。Logistic多因素回归分析显示,年龄〉50岁、有糖尿病病史、肝功能B级以及使用普通无菌纱布是外科手术切口感染的独立危险因素(P〈0.05,P〈0.01)。结论含银离子敷贴可以减少外科手术切口感染的发生率,是一种安全有效的围手术期手术切口护理方式。
Objective To assess the effect of dressing containing silver ion on the decrease of surgical site infection(SSI) after liver surgery. Methods A total of 211 patients who underwent liver surgery in department of oncological surgery of Xuzhou central hospital between January 2011 and December 2015 were enrolled in this study. The patients were randomly divided into dressing containing silver ion group (n = 101 ) and common sterile gauze group (n = 110). Postoperative wound healing situation was observed. Results There was significant difference in the incidence of SSI between common sterile gauze group and dressing containing silver ion group [ 14.55% (16/110) vs 4.95% (5/101) ]. Cuhured bacteria in infected surgical incision were 11 strains of G+ bacteria and 10 strains of G- bacteria in them the most common bacterium was staphylococcus aureus. Logistic multivariate regression analysis showed that age more than 50 years old, having diabetic history,liver function Child B class, using common sterile gauze were the independent risk factors of SSI ( P 〈 0. 05,P 〈 0. 01 ). Conclusion The dressing containing silver ion can reduce the incidence of SSI and is a safe and effective perioperative nursing method.