中文摘要：

报道了芳甲叉双噁唑啉-铜络合物催化三氟甲基丙酮酸酯对吲哚的傅-克烷基化反应,探讨了配体结构、溶剂、温度等因素对反应的影响.研究表明,反应表现出高活性和中等程度以上的对映选择性,吲哚环上取代基对催化反应有重要的影响.提供了一种合成含手性三氟甲基季碳吲哚化合物的新方法.

英文摘要：

This paper reported the reaction of indoles with trifluoromethyl pyruvate catalyzed by heteroaryliden-tethered bis-oxazoline-Cu（II） complex, and the effects of ligand structure, solvent, temperature and different indole substrates on the catalytic reactions were investigated. The results indicate that the reaction furnished high reactivity and moderate to good enantioselectivity, and the substituents on the indole ring have important impact on the reaction. The reaction can afford the indole derivatives with a chiral tertiary carbon center bearing trifluoromethyl substituent in high yields with moderate to good enantioselectivities.