目的:探讨急性缺血性脑卒中患者神经功能损伤程度与脑电图的关系。方法选取2014年8月-2015年8月于贵州省贵阳市第二人民医院收治的急性缺血性脑卒中患者100例作为研究对象。给予依达拉奉+常规治疗。患者行脑电图、神经功能评分测定,对结果进行统计学分析。结果显效组从治疗后72 h开始,各时间点的美国国立卫生研究院卒中评分标准评分与该组治疗前相比较明显好转(P〈0.01)。显效组BSI在治疗后24 h开始较治疗前明显改善,此后72 h、7 d、14 d时间点的BSI均较治疗前明显改善,差异有统计学意义(P〈0.01);非显效组BSI在治疗后24 h及72 h出现明显恶化,差异有统计学意义(P〈0.01);DTABR的反应明显迟于BSI,直到治疗后7 d开始改善,差异有统计学意义(P〈0.01)。非显效组DTABR在治疗后24 h、72 h及7 d出现明显恶化,差异有统计学意义(P〈0.01);缺血性脑卒中患者异常脑电变化的阳性率分布不全相同,前循环脑梗死组(〉1.5 cm)的记录到异常脑电变化的阳性率高于腔隙性脑梗死组(P〈1.5 cm)、后循环脑梗组(〉1.5 cm)。结论脑电图BSI、DTABR指标能比美国国立卫生研究院卒中评分标准更准确、及时反映急性缺血性脑卒中患者治疗后脑功能受损情况的改善情况,脑电图对于评估前循环缺血性脑卒中患者更敏感,值得在临床推广。
Objective To explore the value of electroencephalography (EEG) in evaluation of cerebral function impairment in acute ischemic stroke patients. Methods Totally 100 patients with acute ischemic stroke were selected from Augest 2014 to Augest 2015. All patients were treated with Edaravone plus routine therapy for acute ischemic stroke. EEG and NIHSS scores were used to assess the patients. Results NIHSS scores in the patients with acute ischemic stroke were improved at each time point after 72-hour treatment ( P〈 0.01), while brain symmetry index (BSI) was more sensitive and improved as soon as 24 hours after treatment. The improvement of DTABR was later than BSI and started on the 7th day after treatment ( P〈0.01). The positive rates of abnormal EEG changes were not the same in the patients with ischemic stroke. The positive rate of abnormal EEG changes in the anterior circulation infarction group (diameter > 1.5 cm) was higher than that of the lacunar infarction group (diameter P〈 1.5 cm) and posterior circulation infarction group (diameter > 1.5 cm). Conclusions EEG, especially BSI and DTABR, and NIHSS can accurately and timely reflect the cerebral function improvement in acute cerebral infarction patients, andthey are more sensitive in early diagnosis and prognosis evaluation of acute ischemic stroke. In addition, electroencephalography is more sensitive in evaluation of total anterior circulation infarction.