比较不同来源的多拉菌素对猪消化道线虫和体表寄生虫的驱杀效果,为临床应用该药提供科学依据。将自然感染寄生虫的猪,随机分为高、中、低3个剂量的药物试验组和不给药物治疗对照组,健康无寄生虫感染的猪作为对照,根据试验前和试验后7、14、28、35d猪寄生虫数量和临床变化判定疗效。结果显示,海正多拉与辉瑞通灭对猪的体表寄生虫及消化道线虫均有极好的驱杀作用,临床推荐剂量以中剂量组300μg/kg.BW肌肉注射为宜。
Doramectin products from different sources were compared for their therapeutic efficacy on nematodes and ectozoa in pigs. Pigs naturally infected with nematodes and ectozoa were randomly grouped and treated with high, medium and low doses of doramectin. Control groups included non-treatment pigs and non-infection pigs. Therapeutic efficacy was determined by reduction of parasite numbers and clinical changes on day 0, 7, 14, 28 and 35 post treatments. Both haizheng and tongmie showed excellent desinsectization effects on porcine ectozoa and nematodes. The recommended dose for intramuscular injection was 300 ug/kg weight.