中文摘要：

Sinusoidal obstruction syndrome （SOS）, previouslyknown as hepatic veno-occlusive disease, is a raredisorder in solid organ transplant patients, and is anuncommon complication after liver transplantation.Severe SOS with hepatic failure causes considerablemortality. Tacrolimus has been reported to be anoffending agent, which potentially plays a role inthe pathophysiological process of SOS. SOS due totacrolimus has been reported in lung and pancreatictransplantations, but has never been described in a livertransplant recipient. Herein, we present a case of SOSafter liver transplantation, which was possibly relatedto tacrolimus. A 27-year-old man developed typicalsymptoms of SOS with painful hepatomegaly, ascitesand jaundice after liver transplantation, which regressedfollowing withdrawal of tacrolimus. By excluding otherpossible predisposing factors, we concluded thattacrolimus was the most likely cause of SOS.