中文摘要：

为了寻找高效、安全的杀菌活性化合物，设计并合成了8个N-（4，6-二取代嘧啶-2-基）苯甲酰胺类化合物，其化学结构经。HNMR、IR、LC／MS和元素分析确证。初步生物活性测定结果表明，该类化合物具有一定的杀菌活性，当浓度为25mg／L时，化合物4g对稻瘟病菌Pyricularia oryzae的抑制率达85．1％，化合物4f对小麦赤霉病菌Gibberella zeae的抑制率达92．9％。

英文摘要：

In search of safer and more effective fungicidal compounds, eight N-（4, 6-disubstitued pyrimidin-2-yl）-benzamides were designed and synthesized. Their structures were confirmed by IR, ^1H NMR, LC/MS and elemental analysis. Preliminary bioassay showed that some of the title compounds showed good fungicidal activity, for example, 4g exhibited 85. 1% inhibition rate to Pyricularia oryzae at 25 mg/L and 4f exhibited 92.9% inhibition rate to Gibberella zeae at 25 mg/L.