中文摘要：

目的分析脑卒中患者急性期末临床神经功能缺损程度评分（NFDS）与患者入院初始时的颅内压（ICP）、脑灌注压（CPP）等多种临床因素的相关性,以期得到能提示患者急性期短期预后的临床指标。方法对66例脑梗死患者及43例脑出血患者的急性期末NFDS与患者入院初始时的ICP、CPP、病灶体积、血压、血脂、血糖、纤维蛋白原、发病时间、既往史评分、性别等作单因素相关分析,并在此基础上进一步作多元逐步回归分析,以确定在多因素整体考虑下与急性期末NFDS有统计学显著性意义的临床指标。结果经多元逐步回归分析,脑梗死患者急性期末NFDS与入院时病灶体积,发病后至入院时的时间延迟以及入院后所测的总胆固醇量密切相关,脑出血患者急性期末NFDS与入院时出血的体积,发病后至入院时的时间延迟密切相关。结论在多因素分析中入院时的病灶体积、发病后至入院时的时间延迟,不论是对脑出血还是脑梗死的急性期短期预后而言,都是独立的相关因素;血脂对于脑梗死而言比之对于脑出血更为重要,是脑梗死的急性期短期预后独立的相关因素;血压尚不能提示急性期短期预后。

英文摘要：

Objective To analyze the relationship between the neurological functional deficit scale（NFDS） at the end of the acute period and multi-factors at admission in stroke patients.Methods 109 patients were selected for the report（66 cases were CI and 43 cases were ICH）.The NFDS was used to score the severity of neurological impairment.The relationship between the NFDS at the end of the acute period and multi clinical factors at admission were analyzed with pearson correlation and multiple stepwise regression.ResultsIn the cerebral infarction（CI） patients,the value of TC was independently associated with the extent of NFDS and the volume of focus and the interval from onset were independently associated with the extent of NFDS in the ICH patients.Conclusions The volume of focus and the interval from onset are the commonly influencing factors of NFDS in both CI and ICH patients at the end of the Acute Period;Blood lipids has more important significance to CI patients,than blood pressure.