中文摘要：

电压门钠(Na _v ) 隧道是为在易兴奋的房间的电的信号的产生和繁殖的不可缺少的膜元素。在原核生物的 Na _{最近的年里的 v} 隧道极大地支持这些蛋白质和他们的真核细胞的对应物的机械学的调查。在这份报纸，我们主要在计算研究考察进步，特别模拟研究，在过去的年里的这些蛋白质上。

英文摘要：

Voltage-gated sodium （Nav） channels are indispensable membrane elements for the generation and propagation of electric signals in excitable cells. The successes in the crystallographic studies on prokaryotic Nay chan- nels in recent years greatly promote the mechanistic investigation of these proteins and their eukaryotic counterparts. In this paper, we mainly review the pro- gress in computational studies, especially the simula- tion studies, on these proteins in the past years.