中文摘要：

力生长因子（MGF）是一种自分泌/旁分泌的力敏感因子,在多种软组织受到物理、生化刺激或损伤时都会出现高表达现象,能够在组织修复过程中＂补偿＂应力刺激的不足,通过促细胞增殖、迁移以及分化等有效促进软组织修复。本文总结了MGF在不同软组织内的表达,及其在软组织修复中的作用,同时探讨了MGF在软组织修复应用中存在的问题和面临的挑战。

英文摘要：

Mechano growth factor（MGF）is an autocrine/paracrine factor and sensitive to mechanical stimulation.MGF can be highly expressed in various soft tissues under physical stimuli,biochemistry stimuli or in damaged situation.MGF may＂compensate＂the stress for tissue in the processing of tissue repair.MGF can effectively accelerate the repair of the soft tissue by promoting the proliferation,migration and differentiation of cells.This paper summarizes the MGF expressions in different soft tissues and their functions in soft tissue repair.The paper also discusses current problems and challenges in using MGF to repair the soft tissue.