中文摘要：

目的 比较建立兔肾VX2移植瘤模型的不同方法的优劣。方法 分别用瘤液穿刺法、瘤块液种植法、瘤块包埋法建立兔肾VX2癌模型。采用超声技术动态检测肿瘤体积及CDFI的变化，确定该模型最佳实验干预时段及其血流参数范围。比较各自的成瘤率；观测肾脏肿瘤的大小及其回声、瘤内血管生成以及血流阻抗等指标。结果 瘤块包埋法可建立稳定的兔肾VX2移植瘤模型。B超可以实时、准确、方便的监测肿瘤体积及血流动力学变化。结论 兔肾VX2移植瘤是一种造模方法简便且成瘤率高的肾癌动物模型，采用超声技术能精确、无创的动态监测肿瘤体积变化及血流特征。

英文摘要：

Objective To compare the advantages and disadvantages of several methods to establish the rabbit VX2 carcinoma model. Methods Ultrasound technique was used to confirm the best periods of experiment on the rabbit VX2 carcinoma mode. The rabbit VX2 carcinoma model was established by different ways, such as tumor cells fluids and tumor block transplanting guided by B-ultrasound, tumor block transplanting by operation to compare their successful rate. Kidney size and other indexs were observed. Results Tumor block transplanting by operation was the most successful to establish a steady model. Conclusion The rabbit VX2 carcinoma is one of the biggest animal models for kidney carcinoma＇s experimental research; it is steady and easy to be manipulated.