中文摘要：

共递送抗癌药多柔比星和基因治疗肿瘤可以产生协同治疗作用,提高治疗效果,降低毒性以及克服多柔比星引起的多药耐药性。共递送抗癌药和基因的纳米载体近年成为国内外研究的热点,目前,正在研究的共递送纳米载药体系包括脂质体、纳米粒、胶束等。共递送抗癌药和基因能够弥补抗癌药和基因单独治疗肿瘤的不足,有望进一步研究应用于临床。

英文摘要：

Co- delivery of doxorubicin and gene could achieve synergistic therapeutic effect, enhance therapeutic outcomes, reduce toxicity and reverse multiple drug resistance caused by doxorubicin during cancer therapy. Recently, nano-drug delivery systems for co-delivery of anti-cancer drug and genes have gained much attention worldwide. A variety of nano-drug co-delivery systems such as liposomes, nanoparticles, micelles, etc. are under research and show good prospect of clinical application. Co-delivery of anti-cancer drug and genes could fill up the therapeutic insufficient of both anti- cancer drug and genes, respectively.