角膜的透明特性是其发挥正常生理功能的基础,但在感染、机械及化学损伤等病理情况下可以导致角膜新生血管(corneal neovascularization,CNV)生成,使其失去原有的透明性,严重损害视力。近年来,随着免疫学、分子生物学、生物化学等学科发展,对CNV的认识更加深入,临床上CNV的治疗也不断取得新的突破。本文将主要对抑制角膜新生血管研究方面进行综述。
Corneal transparency is the basis of the normal physiological functions.However,corneal neovascularization(CNV) may occur in the infection,mechanical and chemical injury or under other pathological conditions,which make the cornea lose original transparency and severe visual impairment.In recent years,along with the development of immunology,molecular biology,biochemistry and other disciplines,there is more in-depth understanding on the CNV,and clinical treatment of CNV has made new breakthroughs.This article provides an overview of the inhibition of CNV.