中文摘要：

以高纯空气（O5：N2=21：79）为加压介质，研究了0．5Mpa压力下面包酵母CICC1447和CICC1339细胞生长及细胞内谷胱甘肽、麦角固醇的含量变化。结果表明：加压培养时两株酵母菌的对数生长期延迟出现，对数生长期的持续时间缩短，而且两株菌的比生长速率均明显低于对照组，同时两株菌的倍增时间也较对照组有所延长；压力刺激可显著提高面包酵母细胞内谷胱甘肽（GSH）的含量，但麦角固醇含量的变化却不明显。在0．5MPa压力下保压培养3h时CICC1447胞内谷胱甘肽含量比常压对照组提高了42．6％，而加压3h后麦角固醇舍量比对照组提高了20．1％；加压培养6h时CICC1339胞内谷胱甘肽含量较对照组提高了58．7％，但填麦角固醇含量反而降低。这说明不同的酵母菌对压力刺激的反应是不同的。

英文摘要：

The growth changes of glutathione （GSH） and ergosterol in Saccharomyces cerevisiae （ CICC1447 and CICC1339） were detected under 0.5Mpa pressure with compressed high-pure air （O2：N2 =21： 79）. The results showed that logarithmic phases of the two strains were delayed ; their biomass and special growth rate were lower than those of control sample （0. 1MPa） and the double time were prolonged under 0.5MPa. High - pressure could increase the content of GSH obviously, compared to ambient atmosphere control samples. When the holding time was 3h, the content of GSH and ergosterol in CICC1447 increased 42.6% and 20. 1%, respectively. However, the content of GSH in CICC1339 increased 58.7% when the holding time was 6h, while ergosterol content reduced. The results indicated that different yeast strains have different stress-response mechanism to copy with high-pressure shock.