以海蜇头为原料,通过乙醇分级沉淀、柱层析等分离纯化方法,获得3种组分均一的糖蛋白JGP-Ⅱ、JGP-Ⅲ、JGP-Ⅳ。检测3种糖蛋白对小鼠脾淋巴细胞增殖作用和转化能力的影响,研究其免疫活性。结果表明:3种糖蛋白对小鼠脾淋巴细胞均有增殖作用;对脾淋巴细胞转化能力具有促进作用。
Three kinds of homogeneous glycoprotein(JGP-II,JGP-III and JGP-IV) were isolated from jellyfish oral arms,and their immune activity was studied.The results showed that the three kinds of glycoprotein could improve the proliferation and transformation of mouse spleen lymphocytes.