目的:了解广西两所三甲医院住院患者人芽囊原虫(Blastocystis hominis,B.hominis)的感染情况。方法:收取广西两所三级甲等医院(广西医科大学第一附属医院、附属肿瘤医院)住院患者新鲜粪便,采用改良酸醚沉淀法,镜检定性诊断,用R2.11.1分析住院患者职业及受教育水平各组间B.hominis感染率。结果:两所医院共检查住院患者2 800例,总阳性率为36.6%。一附院与肿瘤医院阳性率分别为22.59%、43.24%。与正常人群感染率相比,住院患者感染率高于正常人群(P〈0.001);肿瘤患者与非肿瘤患者、正常人群感染率相比,差异有统计学意义(P〈0.001);按照消化道疾病患者与非消化道疾病患者分组,两组感染率差异有统计学意义(P〈0.001);按照文化程度、职业划分,两所医院初中及以下学历患者、农民患者感染率较其他患者感染率高且差异有统计学意义(均P〈0.001)。结论:住院患者较正常人群易于感染B.hominis,而其中肿瘤患者和消化道疾病患者则更易于感染B.hominis。
Objective. To investigate the prevalence of inpatients infected with B. hominis in two tertiary hospitals of Guangxi. Methods.The fresh fecal specimens were collected from inpatients of two tertiary hospitals (First Affiliated Hospital of Guangxi Medical University, and Affiliated Tumor Hospital of Guangxi Medical University), and tested for infection by improved centrifugal sedimentation with hydrochloric acid- ether of microscopic diagnosis. Then analyzed the infection of B. hominis across gender, age, occupations, ethnicity, population and education by R2.11.1. Results. A total of 2 800 inpatients were investigated. The overall infection rate was 43.26%. The B. hominis infection rate in First Affiliated Hospital and the Affili- ated Tumor Hospital was 22.59% and 43.24% respectively. ( P 〈0. 001). TheB. hominis infection rate of general inpatients, tumor inpatients, and gastrointestinal inpatients was higher than that of the normal population, non-cancer inpatients and the non-gastrointestinal inpatients( P 〈0. 001). Regarding to the inpatients' education levels and occupation, the infection rates of patients with primary-school education and farmers were significantly higher than those of the other inpatients ( P 〈0.001). Conclusion:Inpatients are more likely infected with B. hominis than normal population, among which cancer patients and patients with digestive diseases are affected more by B. hominis .