中文摘要：

微小RNA（miRNA）是一类内源性长约22个核苷酸的非编码RNA分子，进化中具有高度保守性，在转录后水平调控基因的表达从而在生物过程中发挥重要的作用，生物信息学分析表明人类全部基因的1／3都受到miRNA的调控。目前的研究表明，miRNA广泛调控机体各种生理和病理过程，在生物体发育、心血管疾病以及肿瘤的发生等过程中发挥重要作用。

英文摘要：

MieroRNA （miRNA）is a kind of/endogenous non-coding RNA of 22 nucleotides in length. It is highly conserved and plays an important role in biological processes through the regulation of post-tran- scription gene expression. Bioinformatics analysis shows that a third of all human genes are regulated by miR- NA. Current sudies indicate that miRNAs widely regulate the body＇s physiological and pathological process, and plays an important role in the development of organisms, cardiovascular disease and cancer occurrence.