中文摘要：

提出一种检测早期膝骨性关节炎（ROA,knee osteoarthritis）的方法。首先建立光子在膝关节组织中的传输模型,利用蒙特卡洛（MC,monte carlo）方法模拟近红外光子在三维膝关节组织中的传输;在实验中,改变膝关节模型中软骨的吸收系数和散射系数,记录光子在膝关节表面的光强分布。结果表明,溢出膝关节表面的光子包括未碰撞骨头组织直接溢出的噪音光子和撞击骨头组织后溢出的有意义光子,吸收系数和散射系数的改变会导致膝关节表面光强分布发生变化,因此可通过膝关节表面光强分布变化判断膝关节的早期病变。

英文摘要：

A noninvasive method of diagnosing early knee osteoarthritis is proposed.First,a simplified optical model of knee joint issue irradiated by near infrared light is developed and the propagation of photons in three dimensional（3D）knee joint issue is simulated by Monte Carlo（MC）method.Then,light distributions on the surface of knee joint issues are recorded when absorption or scattering coefficient is altered.The results show that there are useless photons,which directly migrate out of knee issues,and important photons carrying optical parameter information,which collide with bone issue and then migrate out of knee issues.It also shows that changes of absorbance and scattering coefficients will make light distribution different.Therefore,early knee osteoarthritis can be diagnosed by the changes of light distribution.