目前,发生率最高的心率失常被认为是心房纤颤,且该病的发生率随着年龄的增长而上升。伴随着我国人口年龄结构的变化,心房纤颤在我国的发病率逐渐增加。了解该病的发生和发展的机制十分迫切。已经证明,心房重构是该病的重要发生机制。随着研究的加深,研究人员对心房重构与该病的病理学机制有了更加深刻的了解。现就心房纤颤和重构在发病中的机制进行回顾。
Atrial fibrillation is one of the most common arrhythmia. The incidence and mortality increase with age growth. As China entered the aging era, the needs for diagnosis and treatment of this disease are urgent, The mechanism of atrial fibrillation is atrial remodeling, including atrial electrical remodeling and a- trial structural remodeling. Insight into the mechanism of atrial remodeling is necessary for the diagnosis and treatment of atrial fibrillation. With the rapid development of molecular biology, the realization about atrial remodeling has more profound understanding. The research progresses of pathological mechanism in atrial remodeling and atrial fibrillation are reviewed.