目的观察蒲地蓝消炎口服液预防妇产科术后感染的临床疗效,以降低术后感染的发生。方法选取2012年1月-2013年1月医院的200例妇产科手术患者,随机分为试验组和对照组,各100例;两组患者均给予常规抗菌药物治疗,治疗组在常规抗菌药物治疗基础上口服蒲地蓝消炎口服液,评价两组患者的临床疗效。结果试验组总有效率为98.0%,显著高于对照组的85.0%,差异有统计学意义(χ^2=10.865,P〈0.05);试验组患者术后平均最高体温为(37.1±0.2)℃,对照组为(38.0±0.5)℃,两组差异有统计学意义(P〈0.05);试验组退热时间为(42.8±7.8)h,对照组为(43.4±9.1)h,差异无统计学意义;术后发病率试验组为2.0%、对照组为9.0%,两组差异有统计学意义(P〈0.05);两组患者切口甲级愈合率均为100.0%,无一例切口感染发生;两组患者在术后出现轻微泌尿道刺激症,试验组为3.0%,对照组为4.0%,两组比较差异无统计学意义,且尿常规或尿素氮化验结果均无异常。结论蒲地蓝消炎口服液联合抗菌药物治疗相较于单用抗菌药物治疗更能提高妇产科术后患者的生活质量,且安全、有效。
OBJECTIVE To observe the clinical effect of Pudilan antichloristic oral liquid on prevention of postoperative infections in the department of obstetrics and gynecology so as to reduce the incidence of the postoperative infections.METHODS A total of 200 patients who underwent surgeries in the department of obstetrics and gynecology from Jan 2012 to Jan 2013 were enrolled in the study and randomly divided into the experimental group and the control group,with 100 cases in each.Both groups were treated with conventional antibiotics,the treatment group was given Pudilan antichloristic oral liquid based on the conventional antibiotic therapy.The clinical effects were observed and compared between the two groups of patients.RESULTS The total effective rate of the experimental group was 98.0%,significantly higher than 85.0% of the control group(χ^2=10.865,P〈0.05).The highest average postoperative body temperature of the experimental group was(37.1±0.2)℃,the control group(38.0±0.5)℃,and there was significant difference between the two groups(P〈0.05).The antifebrile time of the experimental group was(42.8±7.8)hours,the control group(43.4±9.1)hours,and the difference was not significant.The postoperative morbidity rate of the experimental group was 2.0%,the control group 9.0%,and there was significant difference between the two groups(P〈0.05).The grade A incision healing rates of both groups were 100.0%,and the incision infections did not occur in any case.The patients with postoperative mild irritation of urinary tract accounted for 3.0%in the experimental group,4.0%in the control group,and the difference was not significant;the results of the laboratory test showed that the urine routine and urea nitrogen were normal.CONCLUSION As compared with the single antibiotic therapy,Pudilan antichloristic oral liquid combined with antibiotics therapy can achieve more significant effect on improvement of the quality of life of the patients in the department of obstetrics and gynecology,wh