目的 探讨相位对比法MRI(PC—MRI)测量肺动脉血流的准确性以及临床应用价值。方法 ①选取正常健康志愿者42例,随机分为2组,采用PC—MRI和多普勒超声测量了主肺动脉的内径、最大流速和平均流速。②采用公式分别计算出主肺动脉1个心动周期的血流量。结果 ①PC—MRI和多普勒超声测量主肺动脉的内径分别为(24.4±3、41)mm和(21.5±2.55)mm。②PC—MRI测量主肺动脉的最大流速和平均流速分别为(79.9±24.0)cm/s和(50.3±7.71)cm/s。③多普勒超声测量主肺动脉的最大流速和平均流速分别为(88.8±833)cm/s和(53.7±5.04)cm/s。④PC—MRI测量主肺动脉的血流量为(73.5±6.60)ml,多普勒超声测量主肺动脉的血流量为(69.0±10.6)ml。应用统计学方法成组样本均数t-检验分析2种测量结果,选择检验水平为α为0.05。结论 PC—MRI可以准确测量肺动脉的血流速度和血流量,对评价肺动脉血流动力学的改变具有一定价值。
Objective To investigate the accuracy and applied value of measurement of pulmonary flow velocity with phase-contrast MRI(PC-MRI).Methods ①42 healthy volunteers were divided into 2 groups randomly, one group was examined by PC-MRI, another was examined by doppler ultrasound. The inner diameter, maximum velocity and mean velocity of main pulmonary artery (MPA) were measured ; ②The flow volume of MPA in a cardiac cycle was calculated with formulation. Results ①The inner diameters of MPA measured with PC-MRI and doppler ultrasound were (24.4±3.41) mm and (21.5±2.55) mm respectively ;②The maximum velocity and mean velocity of MPA measured by PC MRI were (79.9±24.0) cm/s and (50.3±7.71) cm/s respeetively;③The maximum velocity and mean velocity of MPA gained by doppler uhrasound was ( 88.8±8.33 ) cm/s and ( 53.7±5.04 ) cm/s resepeetively ; ④The flow volume of MPA in a cardiac cycle measured by PC MRI and doppler ultrasound was (73.5±6.60) ml and (69.0±10.6) ml respectively. The results were analyzed by group sample t - test, and the level of test was 0.05. Conclusion The blood flow velocity and volume of pulmonary artery can be measured accurately by PC-MRI, it is of certain applied value in assessing the pulmonary blood flow dynamies changes.