目的利用频域光学相干断层扫描(SD—OCT)和眼底彩色照相方法测量青光眼视盘旁萎缩区,并比较二者结果的一致性。方法连续收集就诊于中国医科大学附属第一医院眼科的青光眼患者30例(54只眼),进行视盘SD—OCT检查和眼底彩色立体照相。分别测量以视盘为中心6条子午线上视盘旁萎缩区13区宽度并计算平均值,比较2种检查结果的相关性,并进行一致性评价。结果使用眼底彩色照相法和SD—OCT检查法测量青光眼患者眼底视盘旁萎缩区B区平均宽度分别为(229.89±99.82)μm和(224.14±97.10)μm,二者比较无统计学差异(P=0.280)。2种检查方法结果具有高度相关性(r=0.825,p〈0.001),二者间具有良好的一致性(ICE=0.923,95%CI0.870。0.954)。结论利用SD-OCT法与眼底彩色照相法测量青光眼视盘旁萎缩区G区结果具有良好的一致性,可以利用SD-OCT方法测量青光眼视盘旁萎缩区p区。
Objective To measure peripapillary atrophy (PPA) in glaucoma with high- resolution spectral domain-optical coherence tomography (SD-OCT) and conventional color fundus photograph, and compare the consistency of the results between the two irnaging methods. Methods Ato- tal of 30 patients (54 eyes)with glancoma from Department of Opthalroology, the First Hospital, China Medical University were prospectively includ- ed for the study. SD-OCT images and color fundus photographs taken through the region of PPA were qualitatively analyzed. The average width of 13- PPA area in 6 reference lines centered optic nerve were measured using SD-OCT and color fundus photograph. Correlation and agreement between the two measuring methods were analyzed. Results The average width of β- PPA was 229.89± 99.82 μm using color fundus photographs and 224.14±97.10 μm using SD-OCT, respectively. There was no significant difference (P = 0.280). The correlation coefficient was 0.825 between re- sults measured by SD-OCT and color fundus photographs for β-PPA area (P 〈 0.001 ), and agreement between the two methods was good (ICC= 0.923,95% CI 0.870-0.954). Conclusion The correlation and consistency is good between SD-OCT and conventional color fimdus photograph measuring β-PPA area. β-PPA area can be estimated with SD-OCT.