欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
近年来，磁性氧化铁靶向纳米载体作为载药系统引起了人们的关注。磁性靶向载药系统和靶向药物治疗的目的是药物载体载药后，在外部磁场的作用下直接靶向富集在肿瘤或病损组织，杀伤病损细胞，对人体无害或减少毒副作用。本文介绍了影响磁纳米颗粒在体内作用的设计参数，并总结了被广泛应用于氧化铁纳米颗粒的制备，表面修饰，功能化的方法及氧化铁纳米载体在靶向载药体系中的应用。
英文摘要：
Magnetic targeted nanoveetors have attracted a great deal of interest in the application of drug delivery system in recent years. The purpose of magnetic targeted drug delivery and targeted drug therapy is to transport a drug directly to the centre of tumor or lesion sites under an external magnetic field source and thereby treat it deliberately, with no effects or less effects on the body. This review introduces the design parameters that affect magnetic nanoparticles performance in vivo and summarizes the most commonly used synthetic routes, surface modification, functionaliztion of the magnetic iron oxide delivery system, as well as their use in targeted drug delivery.
同期刊论文项目
同项目期刊论文
Photoinactivation effects of hematoporphyrin monomethyl ether on Gram-positive and -negative bacteri
Atomic Force Microscope-Related Study Membrane-Associated Cytotoxicity in Human Pterygium Fibroblast
Sonodynamic Effects of Hematoporphyrin Monomethyl Ether on CNE-2 Cells Detected by Atomic Force Micr
Detection of erythrocytes in patient with elliptocytosis complicating ITP using atomic force microsc
Curcumin induced nanoscale CD44 molecular redistribution and antigen-antibody interaction on HepG2 c
An easy method to detect the kinetics of CD44 antibody and its receptors on B16 cells using atomic f
AFM- and NSOM-based force spectroscopy and distribution analysis of CD69 molecules on human CD4(+) T
Cold Induces Micro- and Nano-Scale Reorganization of Lipid Raft Markers at Mounds of T-Cell Membrane
Nanostructure and nanomechanics analysis of lymphocyte using AFM: From resting, activated to apoptos
NSOM- and AFM-based nanotechnology elucidates nano-structural and atomic-force features of a Y-pesti
Label-free oligonucleotide detection method based on a new L-cysteine-dihydroartemisinin complex ele
Connection between biomechanics and cytoskeleton structure of lymphocyte and Jurkat cells: An AFM st
Electrochemical activity of holotransferrin and its electrocatalysis-mediated process of artemisinin
期刊信息
位置：