中文摘要：

目的探讨强迫症患者的冲动功能与正常人群之间的差异。方法选取符合DSM—IV诊断标准的71例强迫症患者及65例健康对照，采用Barratt冲动性量表（BIS-11），耶鲁-布朗强迫症状量表（Y-BOCS）分别于治疗前和治疗后16周评估其冲动性及症状严重程度。结果治疗前，强迫症组的注意冲动[14（12，16）分]、无计划冲动得分[26（23，28）分]均高于对照组[12（11，13）分][23（20．5，26）分]，差异有统计学意义（P〈0．01）。治疗后，注意冲动与Y—BOCS评分的减分率呈正相关（r=0．443，P=0．018）；Logistic回归分析显示，冲动总分较高，强迫症患者的治疗疗效较好（β=-0．149，P=0．002）。结论强迫症患者存在注意和无计划冲动功能的损害。随着强迫症状改善，其注意冲动功能也有所恢复。治疗前BIS-11总分较高的患者疗效较好。

英文摘要：

Objective To investigate the difference of impulsiveness between patients of obsessive- compulsive disorder（OCD） and healthy controls. Methods Seventy-one patients who met the DSM-IV cri- teria for OCD ,and sixty-five healthy controls were recruited.Impulsiveness and the severity of symptom were assessed with Barratt Impulsivity Scale（ BIS-11 ） and Yale-Brown Obsessive Compulsive Scale（Y-BOCS） hefore and the end of 16th week treatment. Results Before treatment,attentional impulsivity scores（ 14（ 12, 16 ） ） and non-planning impulsivity scores （ 26 （ 23,28 ） ） were significantly higher （ all P〈 0.01 ） in OCD patients compared with controls （ 12 （ 11,13）, 23 （20.5,26） ）. After treament, the reduction rate of attentional impulsivity was positively correlated with the reduction rate of Y-BOCS （ r= 0.443, P= 0.018 ）. Logistic regression analysis reported that with the total scores of BIS-11 increased, the effect of treatment was improved （β=-0.149, P=0.002）. Conclusion Increased attentional and non-planning impulsivity are found in OCD. As the improvement of symptom, the scores of attentional impulsivity are also decreased. The high total scores of BIS-11 are correlated with the efficacy of treatment.