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SKLB1206, a novel orally available multikinase inhibitor targeting EGFR activating and T790M mutants
ISSN号:1535-7163
期刊名称:Molecular Cancer Therapeutics
时间:2012.4
页码:952-962
相关项目:基于三种骨架结构的新型FLT3抑制剂的设计合成和抗急性髓性白血病研究
作者:
Chen, Xin|Zhang, Shuang|Wei, Yu-Quan|Yang, Sheng-Yong|
同期刊论文项目
基于三种骨架结构的新型FLT3抑制剂的设计合成和抗急性髓性白血病研究
期刊论文 24
同项目期刊论文
Discovery of novel Bruton's tyrosine kinase inhibitors using a hybrid protocol of virtual sc
Identification of CK2 inhibitors with new scaffolds by a hybrid virtual screening approach based on
Identification of novel anaplastic lymphoma kinase (ALK) inhibitors using a common feature pharmacop
Structural optimization and structure-activity relationships of N2-(4-(4-Methylpiperazin-1-yl)phenyl
Discovery of N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine derivatives as novel CK1 inhibitors
Discovery of 6-phenylimidazo[2,1-b]thiazole derivatives as a new type of FLT3 inhibitors
Design, Synthesis, and Structure-Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-
A combined molecular docking-based and pharmacophore-based target prediction strategy with a probabi
Structure-Activity Relationship Studies of Pyrazolo[3,4-d]Pyrimidine Derivatives Leading to the Disc
Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3- morpholinopropoxy)quinazolin-
SKLB1028, a novel oral multikinase inhibitor of EGFR, FLT3 and Abl, displays exceptional activity in
Accumulation of FLT3+ CD11c+ dendritic cells in psoriatic lesions and the anti-psoriatic effect of a
Structural modification of an EGFR inhibitor that showed weak off-target activity against RET leadin
Discovery and structure–activity analysis of 4-((5-nitropyrimidin-4-yl)amino)benzimidamide derivativ
SC-535, a novel oral multikinase inhibitor, showed potent antitumor activity in human melanoma model
SKLB-677, an FLT3 and Wnt/beta-catenin signaling inhibitor, displays potent activity in models of FL
银屑病治疗靶点及其药物研发进展
HPLC测定新型抗急性髓性白血病药物SKLB1077的含量
HPLC测定降解过程中的抗银屑病新药Y26
新型抗银屑病药物SKLB628凝胶剂处方的筛选
HPLC测定降解过程中新型靶向药物SKLB-1103的含量
RAS/ERK和PI3K/Akt串线信号网络的敏感性分析研究