中文摘要：

目的：探讨常州地区农村人群糖尿病相关危险因素，为采取相应的干预措施提供参考依据。方法：采用多阶段整群抽样的方法，于2004年6月～2005年9月在常州市武进区共抽取20803例居民进行了基线调查，并在2008年3月～2009年10月成功随访18838例。采用巢式病例对照研究，将本次随访新发101例糖尿病患者作为病例组，按照1：4频数匹配，随机抽取404例年龄性别完全匹配且基线未患糖尿病的对象作为对照，采用单因素和多因素Logistic回归分析糖尿病的相关危险因素。结果：多因素Logistic回归结果显示，高血压、超重（BMI24．00—27．99）、肥胖（BMI≥28）可增加糖尿病的发病风险，而高密度脂蛋白可降低糖尿病的发病风险。结论：高血压、超重（BMI24．00—27．99）与肥胖（BMI≥28）以及较低的高密度脂蛋白可能是常州农村地区糖尿病发病的危险因素，应当针对重点人群干预降低糖尿病发病风险。

英文摘要：

Objective：To investigate the related risk factors of diabetes mellitus （DM） in rural communities of Changzhou and provide a scientific basis for intervention. Methods：Totally 20 803 permanent residents in Wujin district of Changzhou, which were selected by multi-stage cluster sampling method, participated in baseline survey between July 2004 and September 2005. The follow- up was completed in 18 838 people between March 2008 and October 2009. A 1：4 matched nested case-control study was performed in 101 cases with diabetes mellitus. The related risk factors were screened out with single and multi-factor logistic regression. Results：The multi-factor logistic regression showed that hypertension history,overweight （BMI 24.00-27.99）,obesity （BMI ~〉28） increased the risk of diabetes mellitus and high-density lipoprotein reduced the risk. Conclusion：Diabetes is related to hypertension history, overweight（BMI 24.00-27.99）, obesity （BMI ≥28） and low high-density lipoprotein level in rural communities of Changzhou. Integrated intervention on high risk group is an important way to reduce the risk of diabetes mellitus of this group.