中文摘要：

非编码RNA是不参与蛋白质编码的RNA的总称,存在于绝大多数生物体中,非编码RNA在胚胎发育、细胞命运决定、生长调控等方面发挥重要作用.其中短链非编码RNA和长链非编码RNA参与胰腺内分泌细胞发育、胰岛素基因的表达、分泌及利用,与糖尿病的发生密切相关.

英文摘要：

Non-coding RNA is a kind of non-coding protein RNA which is widely present in most of the organisms. Non-coding RNA plays key roles in the embryonic development, cell fate determination, and growth control in the living organisms. MicroRNA and long non-coding RNA involve in differentiation of endocrine cell, insulin gene expression and secretion, and insulin resistance, which are closely associated with diabetes.