C型产气荚膜梭菌是引起仔猪肠毒血症的主要病原菌之一,其致病因子是菌体产生的α、β毒素.作者就α毒素的检测方法、基因克隆与表达调控、结构与功能以及β毒素的分子生物学研究进展进行了介绍.
Clostridium perfringens type C is the most pathogenic bacterium, which can lead to enterotoxaemia of piglets. Its pathogenic factor is alpha-toxin and beta-toxin. Detection methods, gene cloning and expression regulation ,relationship between structure and function of alpha-toxin and molecular biology of beta-toxin were introduced in this article.