中文摘要：

目的观察地黄饮子配合针刺百会穴治疗阿尔茨海默病(AD)的临床疗效。方法将48例阿尔茨海默病患者随机分为试验组和对照组,各24例。试验组采用口服地黄饮子配合针灸治疗,对照组口服盐酸多奈哌齐片。两组患者均治疗30 d为1个疗程,分别于30 d、60 d观察疗效及简易精神状态量表(MMSE)评分情况。结果两组患者治疗前及治疗30 d后MMSE评分比较,差异无统计学意义(P>0.05);治疗60 d后,试验组MMSE评分显著低于对照组,两组比较差异有统计学意义(P<0.05)。两组患者治疗30 d和60 d后,试验组中医疗效明显优于对照组,两组比较差异有统计学意义(P<0.05)。结论地黄饮子配合针刺百会穴治疗AD疗效满意,且远期疗效较好。

英文摘要：

Objective To observe the clinical efficacy of the rehmannia decoction combined acu-puncture at Baihui point on Alzheimer′s disease. Methods 48 cases of AD patients were randomly divided into the test group(n = 24)and the control group(n = 24). Patients in the test group were given oral rehman-nia decoction cooperate acupuncture treatment,the control group was give donepezil HCL tablets orally. Take 30 days as a course of treatment. Observe the efficacy and the MMSE score after 30 days and 60 days and.Results Compare the MMSE score before treatment and after 30 days′treatment,there was no statistically significant differences(P > 0. 05);after 60 days′treatment,the MMSE score of the test group was obviously lower than of the control group,which had statistically significant differences(P < 0. 05);after 30 days′treat-ment and 60 days′treatment,the TCM efficacy of the test group was better than the control group,which had statistically significant differences(P < 0. 05). Conclusion The rehmannia decoction combined acupuncture at Baihui point on Alzheimer′s disease has good effects and showed good long - term effects as well.