表观遗传学药物实验数据如高通量数据、复合物结构和临床实验等数据分布在多个大型数据库中,用户需要搜索多个数据库且难以获取全面的药物信息.该文介绍的人类表观遗传学药物数据库(HEDD)存储和整合表观遗传学药物数据,将有利于表观遗传学药物研究与应用.该文介绍了HEDD系统体系结构,探讨了数据搜索、3D结构显示、数据整合等关键技术,描述了表观遗传学药物库功能和应用方法.
Epigenetic drugs experiment data such as high-throughput sequencing, complex structure, and clinical trials are distributed across multiple large databases. It is difficult for users to obtain com- prehensive epigenetic drug information by searching multiple databases. The human epigenetic drug database (HEDD) focuses on the storage and integration of epigenetic drug information. HEDD will facilitate the study and application of epigenetic drugs. This paper introduces the system architecture of HEDD. The key technologies in the implementation such as data search, 3D structure display and data integration is discussed. The function and application of HEDD are de scribed.