合成了一种新型可降解阳离子聚(氨乙酰氧乙基天冬酰胺)盐酸盐(PAAEA·HCI),并由PAAEA·HCI与羧甲基纤维素钠(NaCMC)水溶液通过静电相互作用得到纳米级聚电解质复合物.同时,研究了该聚电解质溶液浓度、性质、离子强度对复合物粒径和ξ-电位的影响.结果表明,在蒸馏水中,聚电解质浓度为1.0mmol/L、电荷比n+/n-为2制备得到的聚电解质复合物纳米粒子平均粒径为110nm,ξ-电位为35mV,其溶液在4℃时可以稳定保存一周.
A novel polycation, poly(a was prepared starting from L-aspartic acid. minoacetyloxyethylaspartamide) hydrochloride (PAAEA · HCI) The polyelectrolyte complex nanoparticles were ξ-ormed via the electrostatic interaction between poly (aminoacetyloxy-ethylaspartamide) hydrochloride and sodium carboxymethylcellulose. The effects of polyion concentration, solution properties, solution ionic strength on the sizes and zeta potentials of the formed nanoparticles were investigated. The size and ξ-potential of nan oparticles, prepared from a solution of poly(aminoacetyloxyethylaspartamide) hydrochloride in water (1.0 mmol/L) and a solution of sodium carboxymethylcellulose in water (1.0 mmol/L) at n+/n- =2, are 110 nm and 35 mV, respectively. Thus obtained nanoparticles are stable within one week at 4 ℃.