目前,药物治疗仍然是防治水产动物病害的主要方法,但其不合理应用也诱发了大量耐药细菌的产生。如何制定合理的渔用常用药物防耐药用药策略已成为目前研究的重点。系统的综述了耐药突变选择窗理论、中草药防耐药应用及养殖条件影响在防耐药用药策略方向的研究进展。
Currently,the drug treatment is still the main way of preventing and controlling the aquatic animal diseases,but abuse of drugs has also led to a large number of drug-resistant bacteria. How to formulate a reasonable strategies of preventing drug-resistance while applying common drugs in fishery has become the focus on the current study. This paper systematically reviewed the window theory of drugresistant mutation selection,and the research progress on the strategies of preventing drug-resistance such as applying Chinese herbs and the effects of culture conditions.