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补阳还五汤口服和药浴对损伤的大鼠坐骨神经传导速度的影响
  • ISSN号:1671-7856
  • 期刊名称:《中国比较医学杂志》
  • 时间:0
  • 分类:R33[医药卫生—人体生理学;医药卫生—基础医学]
  • 作者机构:[1]河北省唐山市中医医院,河北唐山063000
  • 相关基金:河北省中医药管理局科研计划项目,编号:2012145.
作者: 刘青龙[1]
中文摘要:

目的探讨补阳还五汤口服加药浴对坐骨神经传导速度的影响。方法60只SD大鼠暴露左侧坐骨神经。对照组只钳夹;实验组钳夹并加用补阳还五汤口服及药浴治疗。观察钳夹前和钳夹切除后大鼠坐骨神经传导速度(SNCV)。结果于2、4、6周分别测对照组、实验组的坐骨神经传导速度(SNCV)。各时间段实验组坐骨神经传导速度恢复快于对照组,P〈0.01。结论补阳还五汤口服加药浴对坐骨神经传导速度有明显的促进作用。

英文摘要:

Objective To investigate the effect of oral administration and medicated bath of a Chinese medicine, BuYangHuanWu decoction, on the conduction velocity in injured rat sciatic nerve (SNCV). Methods Sixty healthy adult Sprague-Dawley rats were used in this study. The left sciatic nerve was surgically exposed and injured to prepare the nerve injury models. The rats were divided into two groups. The experimental group received oral administration and medicated bath of BuYangHuanWu decoction. The SNCV was measured both before and 2, 4, 6 weeks after operation. Results The SNCVs in the experimental group were significantly faster than those in the control group at 2, 4, and 6 weeks after treatment ( all were P 〈 0. 01 ). Conclusion The traditional Chinese medicine BuYangHuanWu decoction by oral administration and medicated bath is beneficial to improve the sciatic nerve conduction velocity in rats.

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期刊信息
  • 《中国比较医学杂志》
  • 北大核心期刊(2014版)
  • 主管单位:中国科学技术协会
  • 主办单位:中国实验动物学会 中国医学科学院医学实验动物研究所
  • 主编:秦川
  • 地址:北京市朝阳区潘家园南里5号
  • 邮编:100021
  • 邮箱:b67761337@126.com
  • 电话:010-67779337
  • 国际标准刊号:ISSN:1671-7856
  • 国内统一刊号:ISSN:11-4822/R
  • 邮发代号:82-917
  • 获奖情况:
  • 中国科技论文统计源期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),中国中国科技核心期刊,中国北大核心期刊(2014版)
  • 被引量:7696