[目的]探讨延边地区小学生胰岛素抵抗(IR)对不同代谢危险因素及其聚集性的影响.[方法]采用整群抽样方法抽取延边地区朝鲜族和汉族小学生2 945例作为研究对象,调查一般情况,测定腰围、血压、空腹血糖、三酰甘油(TG)、高密度脂蛋白胆固醇及胰岛素水平.[结果]延边地区IR小学生腹型肥胖、高TG血症、高血压、高血糖及代谢综合征(MS)患病率分别为27.6%,40.0%,33.4%,8.3%及12.2%,与正常对照组比较差异均有统计学意义(P〈0.001).朝鲜族小学生中0,1,2种以上代谢危险因素异常者IR检出率分别为6.0%,13.4%及25.1%,汉族小学生分别为4.8%,7.7%及3.3%;朝鲜族小学生IR与代谢危险因素聚集强度密切相关(P〈0.001).[结论]延边地区小学生IR与不同代谢危险因素及MS密切相关,IR对不同代谢危险因素及MS患病危险的影响程度有所不同.
OBJECTIVETo study the influence of insulin resistance(IR)for the different metabolic risk factors and their clusterings in elementary school students of Yanbian area.METHODSA total of 2 945 of elementary school students in Yanbian area were selected by cluster sampling,and it was measured that the waist circumference,BP and FBG,TG,HL-CD and insulin.RESULTSThe prevalence rates of central obesity,high TG,high BP,hyperglycemia and MS in IR group were 27.6%,40.0%,33.4%,8.3%and12.2%,respectively,and they were higher than that in normal group(P〈0.001).The detection rate of IR with 0,1and 2kinds of abnormal metabolic risk factors was 6.0%,13.4%and 25.1%in Korean-Chinese pupils,and 4.8%,7.7%and 3.3%in Han nationality pupils,and IR had significant relation with the clusterings of metabolic risk factors in Korean-Chinese pupils(P〈0.001).CONCLUSIONIR is closely related to the different metabolic risk factors and MS in the pupils in Yanbian area,and has different influences for different metabolic risk factors and MS.